Description
The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk. Georgios N. Belibasakis Karolinska Institute Department of Dental Medicine Department of Dental Medicine Huddinge Stockholms Ln Sweden Nagihan Bostanci Karolinska Institute Department of Dental Medicine Huddinge Stockholms Ln Sweden Michael A. Curtis King’s College London Dental Institute London United Kingdom George Hajishengallis Univ of Pennsylvania Penn Dental Med Microbio Penn Dental Med Microbio Philadelphia Pennsylvania USA 1. Advances in oral mucosal immunity and the microbiome Georgios N. Belibasakis, George Hajishengallis 2. Trained innate immunity and its implications for mucosal immunity and inflammation George Hajishengallis, Xiaofei Li, Ioannis Mitroulis, Triantafyllos Chavakis 3. Signaling systems in oral bacteria Daniel P. Miller, Richard J. Lamont 4. Origin of Th17 cells in Type 2 Diabetes-Potentiated Periodontal Disease Barbara S. Nikolajczyk, Dolphus R. Dawson III 5. Gingival epithelial cell recognition of lipopolysaccharide Nutthapong Kantrong, Thao T. To, Richard P. Darveau 6. The relationship of Candida albicans with the oral bacterial microbiome in health and disease Martinna Bertolini, Anna Dongari-Bagtzoglou 7. A potential role of Phospholipase 2 group IIA (PLA2-IIA) in P. gingivalis-induced oral dysbiosis Octavio A. Gonzalez, Vanessa Euzebio Alves, Yelena Alimova, Ahmad Al-Attar, Jeffrey L. Ebersole 8. Helicobacter spp. in experimental models of colitis Christoph Mueller, Cheong K. C. Kwong Chung, Martin R. Faderl, Jennifer Brasseit, Daniel Zysset 9. T Helper 17 cells as pathogenic drivers of Periodontitis Nicolas Dutzan, Loreto Abusleme 10. Candida-bacterial biofilms and host-microbe interactions in oral diseases Thais de Cssia Negrini, Hyun Koo, Rodrigo Alex Arthur 11. Comparative analysis of gene expression patterns for oral epithelium-related functions with aging J.L. Ebersole, L. Orraca, M.J. Novak, S. Kirakodu, J. Gonzalez-Martinez, O.A. Gonzalez 12. Neutrophil interaction with emerging oral pathogens: A novel view of the disease paradigm Irina Miralda, Aruna Vashishta, Silvia M. Uriarte 13. Biologically-defined or biologically-informed traits are more heritable than clinically-defined ones: the case of oral and dental phenotypes Cary S. Agler, Kevin Moss, Kamaira H. Philips, Julie T. Marchesan, Miguel Simancas-Pallares, James D. Beck, Kimon Divaris
