Description
This thoroughly revised and updated new edition provides outstanding coverage of the most important aspects of immunology. Assuming no previous knowledge of the subject, the book gives step-by-step detail on topics such as antigens, hypersensitivity, autoimmunity, reproductive immunity and immunodeficiency. There is an accompanying website with supplementary material. Lesley Eales is a respected educational leader. In 2001, she was awarded a prestigious National Teaching Fellowship in recognition of her outstanding contribution to teaching and learning as well as her involvement in improving the practice of immunology. Preface. Preface to the 1st Edition. Glossary. 1 Cells and tissues of the immune system. 1.1 Cells involved in the immune response. 1.2 Lymphoid tissues. 2 Antigens and their receptors. 2.1 Characteristics of antigens and immunogens. 2.2 The major histocompatibility factor. 2.3 Antigen receptors on cells. 2.4 Generation of antigen receptor diversity. 3 The innate immune response. 3.1 The complement cascades. 3.2 Phagocytosis. 3.3 Inflammation. 3.4 Haemostasis and thrombosis. 4 The adaptive immune response. 4.1 Antigen processing and presentation by MHC gene products. 4.2 Antigen processing and presentation by CD1. 4.3 Cell-mediated immunity. 4.4 Cell adaptive immunity. 4.5 Lymphocyte memory. 4.6 The mucosal immune response. 4.7 Tolerance. 5 Abnormalities of the immune system. 5.1 Hypersensitivity. 5.2 Autoimmunity and autoimmune diseases. 5.3 Immunodeficiency diseases. 6 Infection, immunity, immunopathogenesis. 6.1 The innate immune system in infection. 6.2 Infection – the role of the innate immune system. 6.3 Infection – the role of the specific immune response. 6.4 Cytokines in immunity to infection. 7 Immunity and the MHC. 7.1 Transplantation. 7.2 The immunology of reproduction. 8 Other diseases. 8.1 Atherosclerosis. 8.2 Tumour immunology. Answers to “now test yourself!” Index.
