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Epigenetics in Organ Specific Disorders, Volume 34 (Translational Epigenetics)

SKU: 9780128239315

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Epigenetics in Organ Specific Disorders, Volume 34 (Translational Epigenetics), Claudia Gonzaga-Jauregui, 9780128239315

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1. Introduction to epigenetic mechanisms 2. Epigenetic signatures that maintain stemness in pluripotent and mesenchymal stem cells 3. Cell-cell and Cell-matrix interactions mediated by histone deacetylases 4. Enhanced cell proliferation and altered gene expression due to actions of DNA methyltransferases 5. Histone deacetylases and regulation of gene expression during cell proliferation 6. Epigenetic mediators that promote cytoskeletal reorganization and cell migration 7. Inhibition of cellular apoptosis and senescence by unique epigenetic proteins 8. Epigenetic mechanisms involved in the regulation of necrosis and pyknosis 9. Epigenetic control over cell division in pathological conditions 10. Regulated expression of tumor suppressor proteins by DNA methyltransferases during cell cycle progression 11. Role of histone deacetylases in regulating cell cycle progression 12. Phenotype switch and cell differentiation in immune and non-immune cells regulated by different epigenetic mediators 13. Epigenetic pathways that promote cellular autophagy 14. Epigenetic inducers of Cell growth and survival 15. Microbial compounds as potential inducers of epigenetic mechanisms during infections 16. Current epigenetic drugs and their target proteins with potential use in disease treatment 17. Prospects of epigenetic drugs in combination therapy

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