Description
Behet’s syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many aspects need to be considered in a syndrome that presents a wide spectrum of symptoms and for which the therapeutic armamentarium is expanding significantly, with the development of new treatments, not least the so-called biologics. This book offers comprehensive coverage of the disease by some of the world’s leading experts in Behet’s syndrome from all the relevant specialties. Epidemiology, genetics, pathogenesis, organ system involvement, differential diagnosis, novel treatments, surgical management, and prognosis are just some of the topics addressed. Behet’s Syndrome: From Pathogenesis to Treatment will be an invaluable reference for a range of practitioners, researchers, and undergraduates or postgraduates interested in immuno-rheumatology, dermatology, and rare diseases. Preface 1 Behet syndrome.- Preface 2 Behet’s syndrome: the role of patient’s Associations.- The numbers of Behet: a rare disease.- Along the Old Silk Road.- Epidemiology of Behet’s syndrome.- Behet’s syndrome according to classical and population genetics.- Infections, autoimmunity and Behet’s syndrome: what liaison.- Pathogenesis of Behet’s syndrome.- Muco-cutaneous involvement in Behet’s syndrome.- Neurological and neuro-psychological manifestation in Behet’s syndrome.- Ocular involvement and Behet.- Muscle and articular manifestations in Behet’s syndrome.- Cardiovascular issues.- Intestinal Behet Disease.- Audio vestibular involvement in Behet’s disease.- Pregnancy and Behet’s syndrome.- Pediatric Onset of Behet’s syndrome.- Differential Diagnosis.- Classification and Diagnosis Criteria for Behet’s Disease.- Prognosis and Disease Activity.- Old and New Treatment for Behet’s Disease.- Surgical management of Behet’s Disease.
